Outpatient Are there risk factors for MRSA or pseudomonas (e.g. had MRSA or pseudomonas previously or was recently hospitalized and received IV antibiotics in the last 90 days)? Are there comorbidities e.g. chronic heart, lung, liver or kidney disease, diabetes mellitus, alcoholism or asplenia? No: Amoxicillin 1 g tid OR Doxycycline 100 mg bid OR a macrolide if local pneumococcal resistance is < 25%. Macrolide options include: Azithromycin 500 mg on day 1 then 250 mg daily OR Clarithromycin ER 1g daily OR Clarithromycin 500 mg bid. Note that the strongest recommendation is for amoxicillin, followed by a conditional recommendation for doxycycline (there is limited data for oral doxycycline use…